
Jason Westin, MD, FASCP, the director of the Lymphoma Clinical Research Program at University of Texas MD Anderson Cancer Center, discussed the implications of data he presented at ASCO’s 2023 conference.
Jason Westin, MD, FASCP, the director of the Lymphoma Clinical Research Program at University of Texas MD Anderson Cancer Center, discussed the implications of data he presented at ASCO’s 2023 conference.
The assistant professor at MD Anderson Cancer Center discussed new data she presented at the 2023 ASCO Meeting.
Data from a phase 1/2 clinical trial of NRTX-1001 were presented at the ISSCR 2023 Annual Meeting.
The director of the Lymphoma Clinical Research Program at University of Texas MD Anderson Cancer Center discussed recent and ongoing studies that are upending the paradigm in LBCL care.
The assistant professor of medicine at University of Alabama – Birmingham discussed efficacy findings on BMS-986983 and more research to be done.
The director of University of Washington Medicine’s Cancer Vaccine institute discussed the importance of continuing to develop new CAR-T approaches in the ovarian cancer field despite initial setbacks.
Two of 6 patients in the WM cohort achieved a complete response and 16 of 20 patients in the FL cohort achieved a complete response.
The assistant professor of medicine in the Division of Blood and Marrow Transplantation and Cellular Therapy at Stanford University discussed potential methods for optimizing CAR-T efficacy that could be explored in the future.
The phase 1/2 Euplagia-1 trial is currently ongoing in Europe.
Betty Woo, the vice president and general manager of cell, gene, & advanced therapies at Thermo Fisher Scientific, discussed the challenges that exist in gene therapy and cell therapy manufacturing and potential solutions.
The assistant professor of medicine at University of Alabama – Birmingham discussed new data from the first-in-human trial of the CAR T-cell therapy.
The assistant professor of medicine in the Division of Blood and Marrow Transplantation and Cellular Therapy at Stanford University discussed the safety and efficacy results he presented at EHA’s 2023 congress.
The associate professor at Medical College of Wisconsin discussed new findings from the CARTITUDE-4 study.
The objective response rate among patients treated at DL2 and DL3 who were evaluable for efficacy was 57%.
The therapy seems to have a similar benefit in the first patient with TDT in the EdiTHAL trial.
Sang Yoon Moon, PhD, postdoctoral Research Associate, Lions Eye Institute, discussed research with CRISPRa in human fibroblast cultures.
Among 101 patients included in the efficacy analysis, the ORR was 96% and the CR rate was 74.3%.
The director of University of Washington Medicine’s Cancer Vaccine institute discussed results from a phase 1 study presented at ASCO’s 2023 conference.
Follow-up data up to 3 years showed supraphysiologic levels of blood IDUA and decrease of GAGs.
The PhD candidate from University of North Carolina – Chapel Hill discussed preclinical research presented at ASGCT 2023.
The associate professor at Medical College of Wisconsin discussed the rationale for the CARTITUDE-4 study and its latest updates.
The study has enrolled 17 patients as of May 2023 and enrollment is expected to complete by the end of 2024.
New overall survival analysis data on Yescarta from ZUMA-7 were presented at the ASCO 2023 meeting.
The associate professor at University College London also discussed unmet needs that remain in r/r B-ALL and another presentation of interest at ASCO’s 2023 conference.
The professor of medicine and pediatrics at Washington University in St. Louis discussed evaluating afami-cel in the SPEARHEAD-1 trial.
Among 19 patients with r/r B-ALL included in the analysis, all 19 achieved a CR or CRi.
Safety findings were also improved when compared with the previous CARTITUDE-1 study, suggesting the therapy may be better tolerated in earlier lines of therapy.
The director of the Lymphoma Clinical Research Program at University of Texas MD Anderson Cancer Center discussed the implications of overall survival data that he presented at ASCO’s 2023 conference.
The study began enrollment in January 2023.
Additionally, promising efficacy signals were reported—namely response rates and disease control rates—in the phase 1 clinical trial (NCT04429087) data that were presented at the 2023 ASCO Annual Meeting.