Neurology

The CGTLive^™ Neurology specialty topic page houses video interviews with key opinion leaders in the field of neurology about the latest relevant FDA actions, clinical guideline updates, and clinical trial findings related to cell therapies, gene therapies, and engineered and regenerative medicines developed for neurologic disorders and diseases. It also contains up-to-date clinical news coverage in the field of gene and cell therapy for central nervous system disorders.

Latest News

Alzheimer Disease Awareness Month 2024: Looking Back at a Year of Progress in Cell and Gene Therapy

By CGTLive Staff

November 24th 2024

In observance of Alzheimer Disease Awareness Month, held annually in November, we took a look back at the past year's news and expert insights in cell and gene therapy for Alzheimer disease.

CGTLive®’s Weekly Rewind – November 22, 2024

By CGTLive Staff

November 22nd 2024

Bhagirathbhai R. Dholaria, MD, an associate professor of medicine in malignant hematology & stem cell transplantation at Vanderbilt University Medical Center

Evaluating Allogeneic CAR-T P-BCMA-ALLO1 in R/R Multiple Myeloma

By Bhagirathbhai Dholaria, MBBS
Noah Stansfield

November 21st 2024

Around the Helix: Cell and Gene Therapy Company Updates – November 20, 2024

By Noah Stansfield

November 20th 2024

Sophie Olivier, MD, the chief medical officer of Atamyo

Atamyo Therapeutics' Gene Therapy ATA-200 Cleared for US Trial in LGMD Type 2C/R5

By Noah Stansfield

November 19th 2024

Latest CME Events & Activities

Community Practice Connections™: 5th Annual Precision Medicine Symposium – An Illustrated Tumor Board

Fighting Disparities and Saving Lives: An Exploration of Challenges and Solutions in Cancer Care

More News

CGTLive’s Weekly Rewind – June 17, 2022

CGTLive Staff

June 17th 2022

Review top news and interview highlights from the week ending June 17, 2022.

Vutrisiran Approved for hATTR Amyloidosis

Marco Meglio

June 16th 2022

The approval came earlier than the recently extended PDUFA date of July 24, 2022.

Around the Helix: Cell and Gene Therapy Company Updates – June 15, 2022

Victoria Johnson

June 15th 2022

Catch up on the latest news, breakthroughs, and announcements from biotechnology companies making advancements in cell and gene therapies.

Clinical Hold Lifted on Homology’s pheNIX Trial for Phenylketonuria

Victoria Johnson

June 14th 2022

The trial was placed on hold after elevated liver function test scores.

CGTLive’s Weekly Rewind – June 10, 2022

CGTLive Staff

June 10th 2022

Review top news and interview highlights from the week ending June 10, 2022.

Eli-Cel Earns Unanimous FDA AdComm Vote Supporting Risk-Benefit in CALD

Victoria Johnson

June 9th 2022

The FDA's Cellular, Tissue, and Gene Therapies Advisory Committee voted in favor of the benefits of bluebird bio's eli-cel in patients with cerebral andrenoleukodystrophy despite substantial safety concerns.

Around the Helix: Cell and Gene Therapy Company Updates – June 8, 2022

Victoria Johnson

June 8th 2022

Catch up on the latest news, breakthroughs, and announcements from biotechnology companies making advancements in cell and gene therapies.

CGTLive’s Weekly Rewind – June 3, 2022

Victoria Johnson

June 3rd 2022

Review top news and interview highlights from the week ending June 3, 2022.

Around the Helix: Cell and Gene Therapy Company Updates – June 1, 2022

Victoria Johnson

June 1st 2022

Catch up on the latest news, breakthroughs, and announcements from biotechnology companies making advancements in cell and gene therapies.

Expediting the Development of Patient-Specific iSPC Cell Therapies

Stefan Braam, PhD

May 30th 2022

Stefan Braam, PhD, chief executive officer of Ncardia and Cellistic discussed the companies’ work in the cell therapy space.

CGTLive’s Weekly Rewind – May 27, 2022

CGTLive Staff

May 27th 2022

Review top news and interview highlights from the week ending May 27, 2022.

Developing Safer Viral Vectors for Gene Therapy

Victoria Johnson

May 26th 2022

The chief executive officer of Ring Therapeutics, Tuyen Ong, MD, discussed the potential of anellovirus vectors for use in gene therapy.

Amy Pooler, PhD, on Improving Gene Delivery to the CNS

Amy Pooler, PhD

May 26th 2022

The vice president of neuroscience at Sangamo Therapeutics discussed identifying novel capsids with improved neuronal transduction to the CNS.

Around the Helix: Cell and Gene Therapy Company Updates – May 25, 2022

Victoria Johnson

May 25th 2022

Catch up on the latest news, breakthroughs, and announcements from biotechnology companies making advancements in cell and gene therapies.

Gene Therapy May Eliminate Need for ERT in Late-Onset Pompe Disease

Victoria Johnson

May 25th 2022

All study participants met criteria to remain off enzyme replacement therapy through 104 weeks after treatment.

Carsten Bönnemann, MD, on Identifying At-Risk Genotypes for DMD Gene Therapy

Carsten G. Bönnemann, MD

May 23rd 2022

The senior investigator from NINDS discussed findings investigating serious AEs across different trials.

Gene Therapy for AADC Deficiency Receives Positive CHMP Opinion

Victoria Johnson

May 23rd 2022

The positive opinion was based on findings from studies conducted in Taiwan.

CGTLive’s Weekly Rewind – May 20, 2022

CGTLive Staff

May 20th 2022

Review top news and interview highlights from the week ending May 20, 2022.

DMD Gene Therapy Shows Continued Microdystrophin Expression

Victoria Johnson

May 20th 2022

Motor and pulmonary function have stabilized or improved in participants treated with SGT-001.

Around the Helix at ASGCT: Cell and Gene Therapy Company Updates – May 18, 2022

CGTLive Staff

May 18th 2022

Catch up on the latest news and announcements in cell and gene therapies presented at the annual ASGCT meeting.

Analysis Elucidates Lentiviral Vector-Mediated Myelodysplastic Syndrome Cases

Victoria Johnson

May 18th 2022

Multiple insertions were observed in affected participants, including insertions in the MECOM and PRDM16 genes.

Improvements in Developmental Milestones Observed With GM1 Gangliosidosis Gene Therapy

Alicia Bigica

May 18th 2022

Data from 2 patients dosed in the Imagine-1 clinical trial were presented in a late breaking session at ASGCT 2022.

At-Risk Genotypes for DMD Gene Therapy Identified

Victoria Johnson

May 17th 2022

Trial sponsors Pfizer, Sarepta, Genethon, and Solid Biosciences organized a group of experts to investigate shared serious AEs.

Improved Function Observed Following Mini-Dystrophin Gene Therapy in DMD

Alicia Bigica

May 17th 2022

Study sponsor Pfizer recently announced the launch of a phase 3 trial in patients with Duchenne muscular dystrophy.

CGTLive’s Weekly Rewind – May 13, 2022

CGTLive Staff

May 13th 2022

Review top news and interview highlights from the week ending May 13, 2022.

RNA CAR T-Cell Therapy for Myasthenia Gravis Shows Benefits in Early Results

Alicia Bigica

May 12th 2022

Late-breaking interim data were presented at the 14th Myasthenia Gravis Foundation of America (MGFA) International Conference on Myasthenia and Related Disorders.

Around the Helix: Cell and Gene Therapy Company Updates – May 11, 2022

CGTLive Staff

May 11th 2022

Catch up on the latest news, breakthroughs, and announcements from biotechnology companies making advancements in cell and gene therapies.