Nilanjan Ghosh, MD, PhD, on Paving the Way for CAR T Therapies in Lymphomas

Video

The chief of the lymphoma division and oncologist at Levine Cancer Institute discussed work that needs to be done to support the use of CAR T therapy.

“Some work that needs to be done would be development of products which have lower manufacturing time, another would be a more rapid process for financial clearance for commercial parties. We need to understand that the disease is aggressive in many cases, and we just can't wait 4 weeks to get clearance. Another thing would be building relationships with physicians and educating them about indications for CAR T.”

The last few years have seen chimeric antigen receptor (CAR) T-cell therapy approvals in hematologic malignancies including lisocabtagenemaraleucel (Breyanzi), axicabtagenecliolecleucel (Yescarta), brexucabtageneautoleucel (Tecartus) and ciltacabtageneautoleucel (Carvykti). With these approvals, clinicians are beginning to see the long-term impact of these treatments in the clinic

Nilanjan Ghosh, MD, PhD, chief of the lymphoma division and oncologist at Levine Cancer Institute, is one such clinician with first-hand experience with cell therapies in lymphoma. CGTLive spoke to Ghosh to learn more about work that needs to be done to support the growing prominence of CAR T-cell therapies in cancer treatment and future therapies to come to market. He also noted some questions that remain to be researched with these cell therapies.

Recent Videos
Ben Samelson-Jones, MD, PhD, assistant professor pediatric hematology, Perelman School of Medicine, University of Pennsylvania and Associate Director, Clinical In Vivo Gene Therapy, Children’s Hospital of Philadelphia
Manali Kamdar, MD, the associate professor of medicine–hematology and clinical director of lymphoma services at the University of Colorado
Steven W. Pipe, MD, a professor of pediatric hematology/oncology at CS Mott Children’s Hospital
Haydar Frangoul, MD, the medical director of pediatric hematology/oncology at Sarah Cannon Research Institute and Pediatric Transplant and Cellular Therapy Program at TriStar Centennial
David Barrett, JD, the chief executive officer of ASGCT
Georg Schett, MD, vice president research and chair of internal medicine at the University of Erlangen – Nuremberg
David Barrett, JD, the chief executive officer of ASGCT
Bhagirathbhai R. Dholaria, MD, an associate professor of medicine in malignant hematology & stem cell transplantation at Vanderbilt University Medical Center
Caroline Diorio, MD, FRCPC, FAAP, an attending physician at the Cancer Center at Children's Hospital of Philadelphia
Related Content
© 2024 MJH Life Sciences

All rights reserved.