Dr. Maloney on CAR T-Cell Product in B-Cell Lymphoma
David Maloney, MD, PhD, professor of medicine, Division of Oncology, University of Washington, Clinical Research Division, Fred Hutchinson Cancer Research Center, discusses the preliminary safety data of the chimeric antigen receptor (CAR) T-cell product, JCAR017, in relapsed/refractory aggressive B-cell lymphoma.
David Maloney, MD, PhD, professor of medicine, Division of Oncology, University of Washington, Clinical Research Division, Fred Hutchinson Cancer Research Center, discusses the preliminary safety data of the chimeric antigen receptor (CAR) T-cell product, JCAR017, in relapsed/refractory aggressive B-cell lymphoma.
JCAR017 is directed against CD19 and is in multicenter clinical trials for patients with aggressive large B-cell lymphoma. The product is different from other CAR T cells since it targets a selected population, explains Maloney.
According to Maloney, being able to give the T cells in a defined mixture of CD4 and CD8 cells creates a better relationship between the dose response and the dose toxicity.
World Pancreatic Cancer Day 2024: Looking Back at Progress in Cell and Gene Therapy
November 21st 2024In observance of World Pancreatic Cancer Day, held on the third Thursday of November each year, we took a look back at the past year's news in cell and gene therapy for pancreatic cancer indications.
