CGTLive’s Weekly Rewind – September 2, 2022
Review top news and interview highlights from the week ending September 2, 2022.
Welcome to CGTLive’s Weekly Rewind! We’ve compiled 5 highlights from this week’s coverage of advances in gene and cell therapies, including FDA actions, notable research, and interviews with experts across the field.
1. Iovance Starts BLA Submission of Lifileucel for Advanced Melanoma
The tumor-infiltrating lymphocyte therapy has shown efficacy in the phase 2 C-144-01 trial.
2. CARsgen Advances Autologous CAR T Therapies in Multiple Myeloma, Advanced Gastric Cancer
The company has initiated the world’s first confirmatory phase 2 trial of a CAR T-cell therapy in solid tumors.
3. Mark Forman, MD, PhD, on ICM Administration of Gene Therapy in Frontotemporal Dementia
The chief medical officer of Passage Bio discussed the phase 1/2 upliFT-D study of PBFT02.
4. FDA Recognizes CRISPR Therapy for Treatment of Hereditary Angioedema
The in vivo genome-editing therapy is the first gene therapy to be evaluated in a clinical trial for preventing HAE attacks.
5. Phase 3 Heart Failure Cell Therapy Trial Receives Go-Ahead from DSMB
The risk-benefit assessment determined that there are no significant safety concerns.
Evaluating Allogeneic CAR-T P-BCMA-ALLO1 in R/R Multiple Myeloma
November 21st 2024Bhagirathbhai R. Dholaria, MD, an associate professor of medicine in malignant hematology & stem cell transplantation at Vanderbilt University Medical Center, discussed interim data from the phase 1/1b clinical trial evaluating Poseida's CAR-T.
World Pancreatic Cancer Day 2024: Looking Back at Progress in Cell and Gene Therapy
November 21st 2024In observance of World Pancreatic Cancer Day, held on the third Thursday of November each year, we took a look back at the past year's news in cell and gene therapy for pancreatic cancer indications.
