CGTLive’s Weekly Rewind – July 15, 2022

Article

Review top news and interview highlights from the week ending July 15, 2022.

Welcome to CGTLive’s Weekly Rewind! We’ve compiled 5 highlights from this week’s coverage of advances in gene and cell therapies, including FDA actions, notable research, and interviews with experts across the field.

1. ATA188 Shows No Significant Improvements in MS, Study to Continue

There were not enough data at 6 months to predict expanded disability status scale (EDSS) improvements after treatment.

2. First Patient With Mesial Temporal Lobe Epilepsy Dosed With Neural Cell Therapy

Patient recruitment for the clinical trial is currently underway at epilepsy centers throughout the US.

3. First Patient With Familial Hypercholesteremia Dosed With Base-Editing Therapy

Verve Therapeutics is currently conducting a clinical trial in New Zealand and expects to be able to open trials in the UK and US later in 2022.

4. TCR T Cell Therapy for HBV-Related Liver Cancer Cleared for US Trial

SCG101 will be evaluated in trials across China, Singapore, and the US.

5. Legend Biotech Drops Lymphoma CAR T-Cell Therapy

Legend Biotech seeks to prioritize other product candidates in its pipeline.

Recent Videos
Manali Kamdar, MD, the associate professor of medicine–hematology and clinical director of lymphoma services at the University of Colorado
Ben Samelson-Jones, MD, PhD, assistant professor pediatric hematology, Perelman School of Medicine, University of Pennsylvania and Associate Director, Clinical In Vivo Gene Therapy, Children’s Hospital of Philadelphia
Manali Kamdar, MD, the associate professor of medicine–hematology and clinical director of lymphoma services at the University of Colorado
Steven W. Pipe, MD, a professor of pediatric hematology/oncology at CS Mott Children’s Hospital
Haydar Frangoul, MD, the medical director of pediatric hematology/oncology at Sarah Cannon Research Institute and Pediatric Transplant and Cellular Therapy Program at TriStar Centennial
Bhagirathbhai R. Dholaria, MD, an associate professor of medicine in malignant hematology & stem cell transplantation at Vanderbilt University Medical Center
Caroline Diorio, MD, FRCPC, FAAP, an attending physician at the Cancer Center at Children's Hospital of Philadelphia
R. Nolan Townsend; Sandi See Tai, MD; Kim G. Johnson, MD
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