CGTLive®’s Weekly Rewind – August 9, 2024

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Review top news and interview highlights from the week ending August 9, 2024.

CGTLive®’s Weekly Rewind

CGTLive®’s Weekly Rewind

Welcome to CGTLive®’s Weekly Rewind! We’ve compiled 5 highlights from this week’s coverage of advances in gene and cell therapies, including FDA actions, notable research, and interviews with experts across the field.

1. Indapta to Evaluate g-NK Therapy in Trial for Progressive Multiple Sclerosis

The trial evaluating the safety and tolerability of IDP-023 will be led by Stanford and UCSF.

2. Joshua M. Hare, MD, on Working to Address Unmet Needs in Alzheimer Disease With Lomecel-B Cell Therapy

The cofounder and chief science officer of Longeveron discussed working to show potential benefits in a follow-up phase 3 trial.

3. FDA Modifies CAR-T Risk Strategies to Lower Healthcare Burden

A recent study also recommended a shorter, more flexible monitoring period post-CAR–T therapy.

4. David Dimmock, MBBS, on a Promising Case Study of Ultra-Rare, AI-Guided, ASO Development

The chief medical officer at Creyon Bio discussed findings from a treated patient with a TNP02 missense mutation.

5. Pivotal Bria-IMT Trial Hopes to Support BLA for Advanced Metastatic Breast Cancer

BriaCell initiated the pivotal phase 3 BRIA-ABC trial in October 2023.

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Ben Samelson-Jones, MD, PhD, assistant professor pediatric hematology, Perelman School of Medicine, University of Pennsylvania and Associate Director, Clinical In Vivo Gene Therapy, Children’s Hospital of Philadelphia
Manali Kamdar, MD, the associate professor of medicine–hematology and clinical director of lymphoma services at the University of Colorado
Steven W. Pipe, MD, a professor of pediatric hematology/oncology at CS Mott Children’s Hospital
Haydar Frangoul, MD, the medical director of pediatric hematology/oncology at Sarah Cannon Research Institute and Pediatric Transplant and Cellular Therapy Program at TriStar Centennial
Bhagirathbhai R. Dholaria, MD, an associate professor of medicine in malignant hematology & stem cell transplantation at Vanderbilt University Medical Center
Caroline Diorio, MD, FRCPC, FAAP, an attending physician at the Cancer Center at Children's Hospital of Philadelphia
R. Nolan Townsend; Sandi See Tai, MD; Kim G. Johnson, MD
Paul Melmeyer, MPP, the executive vice president of public policy & advocacy at MDA
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