Advancing Gene and Cell Therapies for Brain Cancer

Article

May is Brain Cancer Awareness Month, and the ACGT is raising awareness of the potential of the human immune system when combined with cell and gene therapy to defeat brain tumors.

Brain cancer is one of the deadliest and most difficult-to-treat cancers. Surgery is difficult due to the sensitivity of the brain, and chemotherapy and radiation have limited effectiveness, in addition to a long list of side effects.

brain cancer statistics

For this reason, many cancer experts, patients, caregivers and more are researching and learning more about cell and gene therapy for brain cancer. This novel type of cancer treatment harnesses the power of our own immune system to fight cancer naturally with less harm to healthy tissue than chemotherapy and radiation.

As May is Brain Cancer Awareness Month, Alliance for Cancer Gene Therapy (ACGT) is spending the month raising awareness of the potential of the human immune system when combined with cell and gene therapy to defeat brain tumors. Scientists can make genetic changes to our immune system to help it find and fight brain cancer cells – creating a “living medicine” that not only can wipe out cancer but also prevent it from returning.

This type of treatment is already FDA-approved for several blood cancers, such as lymphoma and leukemia, and it’s in testing for several types of solid tumors.

In 2001, Alliance for Cancer Gene Therapy (ACGT) was founded as one of the first and only nonprofit organizations committed to pursuing advancements in cancer cell and gene therapy. Over the past 2-plus decades, ACGT has awarded 67 research grants totaling $34.2 million to 63 of the brightest scientists.

The foundation is committed to advancing brain cancer research involving cell and gene therapies by funding scientists who are trying to develop cures for this cancer. Even in the past few years, there has been major progress in developing therapies for brain tumors.

Read more about ACGT’s efforts to cure brain cancer on the foundation’s website.

Recent Videos
Alfred L. Garfall, MD, MS, associate professor of medicine (hematology-oncology) and director, Autologous Hematopoietic Cell Transplantation, Cell Therapy and Transplant Program, Hospital of the University of Pennsylvania; and section chief, Multiple Myeloma, Division of Hematology/Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania,
Nirav Shah, MD, MSHP, associate professor of medicine, at the Medical College of Wisconsin
Bhagirathbhai R. Dholaria, MD, an associate professor of medicine in malignant hematology & stem cell transplantation at Vanderbilt University Medical Center
Mark Hamilton, MD, PhD, a hematology-oncology and bone marrow transplant (BMT) cell therapy fellow at Stanford University
Sarah Larson, MD, the medical director of the Immune Effector Cell Therapy Program in the Division of Hematology/Oncology at David Geffen School of Medicine at University of California, Los Angeles (UCLA)
Manali Kamdar, MD, the associate professor of medicine–hematology and clinical director of lymphoma services at the University of Colorado
Manali Kamdar, MD, the associate professor of medicine–hematology and clinical director of lymphoma services at the University of Colorado
Manali Kamdar, MD, the associate professor of medicine–hematology and clinical director of lymphoma services at the University of Colorado
Bhagirathbhai R. Dholaria, MD, an associate professor of medicine in malignant hematology & stem cell transplantation at Vanderbilt University Medical Center
Michael Severino on In Vivo Gene Editing With RNA Gene Writers
Related Content
© 2025 MJH Life Sciences

All rights reserved.